• 10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed 1
  • 10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed 2
  • 10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed 3
  • 10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed 4
  • 10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed 5

10 Best Acne Spot Treatments 2022 | UK Dermatologist Reviewed

Acne is not just a teenage problem - no matter how under control your skincare routine is, or how genetically lucky you are, you can't always completely defend yourself from an annoying zit cropping up! Regardless of how tempting it may be to poke, prod, or squeeze, it is always a good idea to go in and treat the spot with a specially formulated treatment.


Seeing as not every day can be a perfect skin day, we will guide you through the elements to look out for when choosing your acne spot treatment. Whether you are looking for a cheap acne treatment, a fast-acting treatment, or simply one that is easy to cover up, we have listed our top 10 products from Amazon, Boots, and John Lewis. We have partnered with Dermatologist Felipe Partarrieu for reviewing and fact-checking the article so that we can deliver you the best information.

This Article's Contributors

Felipe Partarrieu
mybest Editing Team
  • Last updated: 18-05-2022
Table of Contents

Fact-Checked & Approved by Dermatologist Felipe Partarrieu

Fact-Checked & Approved by Dermatologist Felipe Partarrieu

Felipe Partarrieu is a final year dermatology resident, who is GMC registered with a full license to practise in the UK. Specialising in cosmeceuticals, facial skincare, and hair disorders, we worked with Felipe to bring you top quality information to help you make informed buying decisions and understand more about what goes onto your skin.

Compare the Best Acne Spot Treatments

For those after a quick look, here is our Top 5:

  1. Dermalogica - MediBac Clearing Overnight Clearing Gel for £46.00
  2. Zisticka - Killa Spot and Blemish Clarifying Patch for £26.99
  3. Clean & Clear - Advanced Spot Gel for £4.00 
  4. REN Clean Skincare - ClearCalm Non-Drying Spot Treatment for £15.30 
  5. Origins - Super Spot Remover Blemish Treatment Gel for £16.00 

For a more in-depth look at the comprehensive top 10 selection, make sure to read on to learn more about the different types of Acne Spot Treatments available and understand how our ranking was determined.

This article's chosen EC site price listings are reflective of its publishing date.

Image
1
Dermalogica MediBac Clearing Overnight Clearing Gel 1

Dermalogica

2
Zitsticka  Hydrocolloid Acne Patches With Salicylic Acid and Niacinamide 1

Zitsticka

3
Clean & Clear Advanced Spot Gel 1

Clean & Clear

4
REN Clean Skincare ClearCalm Non-Drying Spot Treatment 1

REN Clean Skincare

5
Origins Super Spot Remover Blemish Treatment Gel 1

Origins

6
Murad Rapid Relief Spot Treatment 1

Murad

7
La Roche-Posay Effaclar A.I. Breakout Corrector 1

La Roche-Posay

8
Mario Badescu Drying Lotion 1

Mario Badescu

9
 COSRX  COSRX AC COLLECTION Ultimate Spot Cream 1

COSRX

10
Dots for Spots Original Acne Absorbing Pimple Patches 1

Dots for Spots

Name

MediBac Clearing Overnight Clearing Gel

Hydrocolloid Acne Patches With Salicylic Acid and Niacinamide

Advanced Spot Gel

ClearCalm Non-Drying Spot Treatment

Super Spot Remover Blemish Treatment Gel

Rapid Relief Spot Treatment

Effaclar A.I. Breakout Corrector

Drying Lotion

COSRX AC COLLECTION Ultimate Spot Cream

Original Acne Absorbing Pimple Patches

Features

An Overnight Treatment to Clear Spots by Morning

Our Go-To Acne Patches

Quick and Cost-Effective Spot Treatment That Starts Working Within 4 Hours

A Moisturising Treatment for Those With Sensitive Skin

A Moisturising Treatment for Those With Sensitive Skin

Rapid Spot Treatment That Can Be Worn Under Makeup

A Gentle Formula to Reduce the Appearance of Breakouts From La Roche Posay

Treat Your Acne With This Drying Lotion for Quick Results

A Overnight On-The-Spot Treatment to Reduce and Restore the Skin

Resist Picking With These Handy Dots for Spots

Price£52.83£26.99£4.00£13.07£16.00£17.00£14.87£20.25£24.99£5.99
Key IngredientsSalicylic acid, niacinimide, tea tree oilSalicylic acid, niacinamide, tea tree oilGlycerin, salicylic acidGlycerin, salicylic acid, lactic acidSalicylic acid, witch hazelSalicylic acid, witch hazelPropylene glycol, niacinamideSalicylic acid, sulfur, glycerinSalicylic acid, niacinamide, glycerin-
Best For Clearing Spots, Reducing their Appearance Treating Acne Controlling Blemishes Sensitive Skin Soothing and Reducing SpotsReduce RednessClears Blemishes Recover Affects From Blemishes Reduce Size Of Spots, Restore Areas of ConcernDrawing Moisture from Acne Cysts
Application Type GelStickerGel Cream Gel Cream CreamLotion Cream Hydrocolloid acne stickers
Volume / Quantity 50 ml 8 pcs (16 total) 15 ml15 ml10 ml15 ml15 ml29 ml 30 ml 24 stickers
Link

How to Choose an Acne Spot Treatment in the UK

Key Points to Consider

  1. Prioritise Key Ingredients To Treat Blackheads or Inflammation 
  2. Decide Between Day Or Night Acne Treatments
  3. Opt for Acne Patches If You Are Prone To Picking At Your Spots 

1. Prioritise Key Ingredients Like Salicylic Acid and Niacinamide to Treat Blackheads and Acne Cysts

1. Prioritise Key Ingredients Like Salicylic Acid and Niacinamide to Treat Blackheads and Acne Cysts

If You’re Trying to Clear Blackheads and Whiteheads, BHA Salicylic Acid Is Key

  • Beta-hydroxy acid (BHA): commonly known as salicylic acid, is a powerful exfoliant. If you are trying to clear a whitehead or blackhead, you will definitely want to reach for something containing this ingredient.


  • Salicylic acid: is oil-soluble, allowing it to penetrate deep into the pores. Once there, it will soften and dissolve keratin plugs and any old skin cells that trap dirt and cause zits. 
Felipe Partarrieu
Dermatologist
Felipe Partarrieu

Salicylic acid is an oil-soluble agent, meaning it can reach the deeper portion of the pores and helps to "unclog" them. This makes it a suitable ingredient for targeting the removal of dead skin cells on the surface of oily and blemish-prone skin, as it has some anti-inflammatory properties. 


The best acne to treat with salicylic acid is blackheads and whiteheads. Bear in mind that these effects are more noticeable the more time it is in contact with the skin, so masks or leave-on treatments are more likely to provide better results than face washes.

Look For Niacinamide if You Suffer from Redness and Inflammation

One of the things that will draw the most attention to a spot is the inflammation that can occur around it. When the skin is irritated, the area can become red, almost creating a 'bullseye' effect around your blemish


If you are particularly concerned about inflammation, we strongly advise looking for products that contain niacinamide. Often found in anti-ageing products to minimise the appearance of wrinkles, niacinamide also helps to reduce redness making your spot appear much less apparent. 

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

Niacinamide is a form of Vitamin B3 with sebum-regulating and anti-inflammatory properties, making it a great agent for the control of acne lesions. In addition, niacinamide helps protect the natural barrier of the skin against infection and may have a bacteriostatic effect on Cutibacterium acnes. It has also shown promise in the treatment of acne complications, including pigmentation changes and purported anti-ageing properties while offering some level of UV protection too.

Apply a Treatment With Sulphur to Avoid Acne Cysts and Enlarged Pores

Admittedly, sulfur has fallen out of popularity in recent years, partly due to the fact that it has a somewhat unpleasant fragrance. However, this does not negate its effectiveness as an acne treatment.


If you can withstand the scent, sulfur has anti-fungal and anti-bacterial properties that can help with reducing zits. It is also keratolytic, just like salicylic acid, so it will be able to break down the build up of keratin to prevent zits from forming or your pores getting larger!

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

Sulphur is a naturally occurring amino-rich mineral that has both antimicrobial and anti-inflammatory properties-, and is widely believed to reduce Cutibacterium acnes bacteria on the skin while removing excess oil and dead skin cells. 


All of these properties, alongside its sebum-regulation capacity, make it an option to consider in the treatment of mild-to-moderate acne (whiteheads, blackheads, and papules). It's also worth noting that it's safe to use for pregnant and nursing women.

Witch Hazel and Tea Tree Oil Are Effective Anti-inflammatory Ingredients for Those Who Prefer Natural Skincare

Hamamelis Virginiana Extract, commonly known as witch hazel, comes from a small tree native to North America. Witch hazel has some interesting properties that it shares in common with another tree-derived ingredient, tea tree oil. 


Both tea tree oil and witch hazel have powerful anti-inflammatory properties which aid in reducing redness and are anti-bacterial and anti-fungal. Also helping to prevent the build-up of dirt on the skin's surface.


To keep your skin calm, how about a facial steamer?

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

This extract contains many compounds with anti-inflammatory properties, such as gallic acid and tannins, that have a proven effect on reducing facial erythema (redness) on people with sensitive skin. 


Tea tree oil, also known as malaleuca oil, is composed of more than 100 molecules. Terpinen-4-ol is one of the major components and it exhibits strong anti-inflammatory and antimicrobial activity against different microorganisms affecting the skin, properties that support its use for the treatment of acne.

If You Have Dry Skin, Seek Out Glycerin and Propylene Glycol to Moisturise and Soothe Irritation

Although it is incredibly tempting to try and dry out your zit as quickly as possible, one of the benefits of using a specifically designed acne treatment in the place of a DIY solution is that you can ensure that you are still being kind to your skin.


If you have sensitive or dry skin, we recommend keeping an eye out for the moisturising agents glycerin and propylene glycol. These ingredients are humectants, meaning that they will help maintain and restore moisture to the skin, preventing it from becoming irritated. 


We have comprehensive guides on the best face washes for acne and face masks for acne, too!

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

Glycerin is a natural component of healthy skin, and it's one of the best humectants (together with urea and hyaluronic acid), drawing moisture from the air around us and helping to lock that moisture in the skin. It also helps the skin to shield itself from environmental sources of irritation and enhances the penetration of other active ingredients into the skin’s uppermost layers.

2. Lotions Are Great for Treating Acne While You Sleep, Gels and Creams Can Be Applied With Makeup During the Day

2. Lotions Are Great for Treating Acne While You Sleep, Gels and Creams Can Be Applied  With Makeup During the Day

Topical acne treatments come in a few different formulas, such as gels, lotions, and creams. The type you choose will depend on your preferred application method.


  • Lotions: have a liquid consistency and can be applied lightly either directly onto the target area, or all over the face. These are best for applying at night to work on your acne while you sleep, though we recommend using them together with your usual face cream as they can be quite drying. 

  • Creams: have a heavier viscosity than lotions and tend to have higher levels of active ingredients. These are better for daytime use or applying underneath makeup as they create a barrier on top of the skin to protect against pollution and environmental irritation.

  • Gels: we recommend for intensive acne treatments. They can be harder to cover with makeup, but will provide the best barrier, keeping out nasties and locking in ingredients to target that zit!
Felipe Partarrieu
Dermatologist
Felipe Partarrieu

There are plenty of formulations to suit all tastes and needs and the choice can be overwhelming at times. Gels usually have the highest concentration of active ingredients (think most prescription treatment for acne come as gels) and create a film over the lesions that prevents debris from spreading. Lotions have more water in their formulation and can easily spread, so they can be used as masks or night treatment.

3. Acne Patches and Zit Stickers Create a Barrier if You Are Prone to Picking at Your Spots

 3. Acne Patches and Zit Stickers Create a Barrier if You Are Prone to Picking at Your Spots

Acne stickers or patches are a wonderful choice for people who just can't resist picking at their zits. Picking can be detrimental to your acne recovery as your hands introduce more bacteria to the area. By applying an acne sticker patch after you have cleansed the area, you'll be less tempted to pick as your fingers will no longer have easy access to the spot.


Most acne stickers are transparent and fairly simple to cover with make up. However, there is a huge difference between hydrocolloids and targeted acne patches, so it's important you know the difference before buying.


Hydrocolloids were introduced to the skincare market via the medical field. They are designed to draw out moisture from a specific area, which is great for removing pus and sebum. For more intensive spot treatment, we recommend getting a targeted acne patch. These have micro darts that gently penetrate under the surface of the skin to deliver acne-healing ingredients, like salicylic acid, directly to the source.

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

There are two distinct types of acne patches: hydrocolloid and medicated patches. Hydrocolloid actively absorbs fluids and pus without drying the surrounding skin, and the very same ingredients that make the acne patch stick literally suck the debris and sebum out of a pimple and into the patch. 


Medicated patches are basically "band-aids" that create an occlusive environment for the active ingredients, such as benzoyl peroxide or salicylic acid, to penetrate better and act faster. For early- stage lesions (papules without pus) medicated patches may help minimise inflammation. Once the pimple has pus, it's recommended to switch to a hydrocolloid patch.

10 Best Acne Spot Treatments in the UK

This ranking has been compiled by the writing team at mybest UK via careful evaluation of the points made in the buying guide and thorough research of each product and comparing multiple verified customer reviews across the EC sites used.

1

DermalogicaMediBac Clearing Overnight Clearing Gel

£52.83

Key IngredientsSalicylic acid, niacinimide, tea tree oil
Best For Clearing Spots, Reducing their Appearance
Application Type Gel
Volume / Quantity 50 ml
2

Zitsticka Hydrocolloid Acne Patches With Salicylic Acid and Niacinamide

£26.99

Key IngredientsSalicylic acid, niacinamide, tea tree oil
Best For Treating Acne
Application Type Sticker
Volume / Quantity 8 pcs (16 total)
3

Clean & ClearAdvanced Spot Gel

£4.00

Key IngredientsGlycerin, salicylic acid
Best For Controlling Blemishes
Application Type Gel
Volume / Quantity 15 ml
4

REN Clean SkincareClearCalm Non-Drying Spot Treatment

£13.07

Key IngredientsGlycerin, salicylic acid, lactic acid
Best For Sensitive Skin
Application Type Cream
Volume / Quantity 15 ml
5
Key IngredientsSalicylic acid, witch hazel
Best For Soothing and Reducing Spots
Application Type Gel
Volume / Quantity 10 ml
6

MuradRapid Relief Spot Treatment

£17.00

Key IngredientsSalicylic acid, witch hazel
Best For Reduce Redness
Application Type Cream
Volume / Quantity 15 ml
7

La Roche-PosayEffaclar A.I. Breakout Corrector

£14.87

Key IngredientsPropylene glycol, niacinamide
Best For Clears Blemishes
Application Type Cream
Volume / Quantity 15 ml
8

Mario BadescuDrying Lotion

£20.25

Key IngredientsSalicylic acid, sulfur, glycerin
Best For Recover Affects From Blemishes
Application Type Lotion
Volume / Quantity 29 ml
9

COSRX COSRX AC COLLECTION Ultimate Spot Cream

£24.99

Key IngredientsSalicylic acid, niacinamide, glycerin
Best For Reduce Size Of Spots, Restore Areas of Concern
Application Type Cream
Volume / Quantity 30 ml
10

Dots for SpotsOriginal Acne Absorbing Pimple Patches

£5.99

Key Ingredients-
Best For Drawing Moisture from Acne Cysts
Application Type Hydrocolloid acne stickers
Volume / Quantity 24 stickers

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Written and researched by Hannah Kato

About Specialist Fact-Checked Articles

Felipe Partarrieu
Dermatologist
Felipe Partarrieu

We partner with specialists across various fields to proofread our buying guides to deliver accurate and reliable information. Our specialists do not endorse any products that we recommend.


- mybest UK

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